Tuesday 2 August 2016

The DNA

DNA is a long polymer of deoxyribonucleotides. It is an acidic substance
present in nucleus. DNA was first identified by Friedrich Meischer in 1869.
He named it as "Nuclein". Altmann found these substances to be acidic in
nature, hence he named it nucliec acid.

The length of DNA is usually defined as number of nucleotides or a pair of
nucleotide referred to as base pairs (bp) present in it. This also is the
characteristic of an organism.


For e.g.,
Organisms Genetic material Number of nucleotides or bp
Fhai-X174 Bacteriophage ssDNA, circular 5386 bases
Lamda Phage dsDNA, Linear 48502 bp
Escherichia coli dsDNA, circular 4.6 x 106 bp
Haploid Human Genome dsDNA, Linear 3.3 x 109 bp

Occurrence of DNA
It is an acidic substance first isolated from nucleus of pus cells.
In eukaryotes, DNA occurs inside nucleus and two types of semi-autonomous cell organelle, mitochondria and plastids (e.g., chloroplasts).
Name of the DNA Location inside the cells Feature
Nuclear DNA Inside the Nucleus Nuclear DNA is associated with histone protiens to form chromatin fibres.
Organelle DNA Inside semi-autonomous cell organelle Organelle DNA is without Histone protiens (naked DNA).
Chromosomal DNA Naked DNA embedded in prokaryotic cytoplasm. DNA may be folded with the help of RNA and polyamines.
Plasmids Prokaryotic cytoplasm. Extranuclear or extra-chromosomal small circular DNA.
Check out more types of DNA here : DNA types.
Check out next post for :-
~ What are Nucleotides?
~ What are base pairs (bp)?

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